![]() The poisonous gas hydrogen sulfide is a byproduct of taurine. Taurine helps the body digest fats and oils and is found naturally in bile acids in the gut. They identified a class of bacteria - Deltaproteobacteria - involved in fighting these infections, and further analysis led them to identify taurine as the trigger for Deltaproteobacteria activity. The scientists observed that microbiota that had experienced prior infection and transferred to germ-free mice helped prevent infection with Kpn. Scientists are studying the microbiota with an eye to finding or enhancing natural treatments to replace antibiotics, which harm microbiota and become less effective as bacteria develop drug resistance. Scientists know that microbiota - the trillions of beneficial microbes living harmoniously inside our gut - can protect people from bacterial infections, but little is known about how they provide protection. The finding, published in the journal Cell by scientists from five institutes of the National Institutes of Health, could aid efforts seeking alternatives to antibiotics. Scientists studying the body’s natural defenses against bacterial infection have identified a nutrient - taurine - that helps the gut recall prior infections and kill invading bacteria, such as Klebsiella pneumoniae ( Kpn). Cardiac arrhythmias having no known cause in otherwise healthy people are hypothesized to be symptoms of deficiencies of taurine and arginine.Colorized scanning electron micrograph showing carbapenem-resistant Klebsiella pneumoniae interacting with a human neutrophil. ![]() l-arginine is hypothesized to prevent cardiac arrhythmias by NO stabilization of the sinus node. Endogenous production of taurine and l-arginine may decline in aging perturbing cardiac rhythm, and these "conditional" essential nutrients therefore become "essential" and require supplementation to prevent morbidity and mortality. l-arginine may have anti-arrhythmic properties resulting from its role as a nitric oxide (NO) precursor and from its ability to restore sinus rhythm spontaneously. Arrhythmias may also respond to taurine because it dampens activity of the sympathetic nervous system and dampens epinephrine release. Taurine restored energy and endurance in one of the cases from a debilitated status to normal. Effects of taurine useful in preventing arrhythmias include regulating potassium, calcium and sodium levels in the blood and tissues, regulating excitability of the myocardium, and protecting against free radicals damage. Adding 4-6g of l-arginine immediately terminated essentially all remaining pauses and PACs, maintaining normal cardiac rhythm with continued treatment. ![]() Case histories of people with very frequent arrhythmias are presented showing 10-20g taurine per day reduced PACs by 50% and prevented all PVCs but did not prevent pauses. ![]() We searched for nutrient deficiencies that could cause cardiac arrhythmias, and found literature support for deficiencies of taurine and l-arginine. Elimination of cardiac arrhythmias using oral taurine with l-arginine with case histories: Hypothesis for nitric oxide stabilization of the sinus node.
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